Use of date products in production of oxytetracycline by Streptomyces rimosus.

Oxytetracycline, one of the tetracycline family, is a broadspectrum antibiotic produced by different species of Streptenryces, namely Streptomyees rimosus, Streptonryces capuensis, Streptomyces henetus, and Struptomyces platensis (Finlay et al,i)), The antibiotic is active on Gram-pesitive and negative bacteria, spirochetes, rickettsiae, nd some viruses, Many workers2"i4) have studied factors and chemical ingredients of media favoring the fermeptative formation of oxytetracycline, but no one has used date constituents in the production of oxytetracycline. Dates are local agricultural renewable resources in the Kigndom of Saudi Arabia, and the aim of this work is to use date constituents as nutrients in media for the formation of oxytetra-